Polyclonal Antibody to GluR2 (Ab-880)
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Cull-Candy, S. et al. (2006) Curr. Opin. Neurobiol. 16, 288-297. Hanley JG, et al. (2002) Neuron. 34 (1) : 53-67
Product Specifications
Product Name Alternative
GRIA2|| GluR-2|| GluR-B|| GluR-K2|| AMPA 2
Gene Name
GRIA2
Gene ID
2891
UniProt
P42262
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around aa.878~882 (I-E-S-V-K) derived from Human Glutamate receptor 2.
Target Antigen
GluR2 (Ab-880)
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 100kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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