Polyclonal Antibody to Gab1 (Ab-627)
The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Anders Kallin, et al. (2004) J. Biol. Chem; 279: 17897 - 17904. Hideto Kameda, et al. (2001) Cell Growth Differ; 12: 307. Masaki Osawa, et al. (2002) J. Cell Biol; 158: 773.
Product Specifications
Product Name Alternative
Growth factor receptor bound protein 2-associated protein 1
Gene Name
GAB1
Gene ID
2549
UniProt
Q13480
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Peptide sequence around aa.625~629 (V-E-Y-L-D) derived from Human Gab1.
Target Antigen
Gab1 (Ab-627)
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 110kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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