Polyclonal Antibody to Dab1 (Ab-232)
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Product Specifications
Product Name Alternative
Disabled homolog 1
Gene Name
DAB1
Gene ID
1600
UniProt
O75553
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.230~234 (G-V-Y-D-V) derived from Human Dab1.
Target Antigen
Dab1 (Ab-232)
Clonality
Polyclonal
Applications
IHC
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 80kd, Immunohistochemistry: 1:50~1:100
Isotype
Rabbit IgG
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