Polyclonal Antibody to GABRB1 (Ab-434)
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding a 4, a 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.
Product Specifications
Product Name Alternative
GABA (A) receptor|| GABA (A) R beta-1|| GBRB1|| GABA-RB
Gene Name
GABRB1
Gene ID
2560
UniProt
P18505
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around aa.432~436 (R-A-S-Q-L) derived from Human GABRB1.
Target Antigen
GABRB1 (Ab-434)
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 54kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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