Polyclonal Antibody to cofilin (Ab-3)
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Kobayashi M, et al. (2006) EMBO J 25 (4) : 713-26. Wang Y, et al. (2005) Biol Chem 280 (13) : 12683-9. Smith-Beckerman DM, et al. (2005) Mol Cell Proteomics: 156-68.
Product Specifications
Product Name Alternative
CFL|| CFL1|| COF1|| Cofilin
Gene Name
CFL1
Gene ID
1072
UniProt
P23528
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa. 1~5 (M-A-S-G-V) derived from Human cofilin.
Target Antigen
Cofilin (Ab-3)
Clonality
Polyclonal
Applications
WB, IHC
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 19kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Isotype
Rabbit IgG
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