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Polyclonal Antibody to p21Cip1 (Ab-145)

May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.

Product Specifications

Product Name Alternative

CAP20|| CDK-interacting protein 1|| CDKN1|| CDKN1A|| CDN1A

Gene Name

CDKN1A

Gene ID

1026

UniProt

P38936

Host

Rabbit

Reactivity

Human

Immunogen

Peptide sequence around aa.143~147 (R-Q-T-S-M) derived from Human p21Cip1.

Target Antigen

P21Cip1 (Ab-145)

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 21kd, Western blotting: 1:500~1:1000

Isotype

Rabbit IgG

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