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Polyclonal Antibody to ASK1 (Ab-83)

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.

Product Specifications

Product Name Alternative

ASK-1|| M3K5|| MAP3K5|| MAPK/ERK kinase kinase 5|| MAPKKK5

Gene Name

MAP3K5

Gene ID

4217

UniProt

Q99683

Host

Rabbit

Reactivity

Human

Immunogen

Peptide sequence around aa.81~85 (G-S-S-V-G) derived from Human ASK1.

Target Antigen

ASK1 (Ab-83)

Clonality

Polyclonal

Applications

WB, IHC, IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 155kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Isotype

Rabbit IgG

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