Polyclonal Antibody to CREB (Ab-133)
This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.
Product Specifications
Product Name Alternative
CREB-1|| CREB1
Gene Name
CREB1
Gene ID
1385
UniProt
P16220
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Peptide sequence around aa. 131~135 (R-P-S-Y-R) derived from Human CREB.
Target Antigen
CREB (Ab-133)
Clonality
Polyclonal
Applications
WB, IHC
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 43kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Isotype
Rabbit IgG
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