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Polyclonal Antibody to Rel (Ab-503)

The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NF-KB family, which also includes RELA (MIM 164014), RELB (604758), NF-KB1 (MIM 164011), and NF-KB2 (MIM 164012) . These proteins are related through a highly conserved N-terminal region termed the 'Rel domain, ' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NF-KB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 (PubMed18037997) ) .

Product Specifications

Product Name Alternative

C-Rel

Host

Rabbit

Reactivity

Human

Immunogen

Peptide sequence around aa.501~505 (T-S-S-D-S) derived from Human Rel.

Target Antigen

Rel (Ab-503)

Clonality

Polyclonal

Applications

IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 78kd, Immunofluorescence: 1:100~1:200

Isotype

Rabbit IgG

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