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Polyclonal Antibody to Raf1 (Ab-259)

Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.

Product Specifications

Product Name Alternative

C-RAF|| C-Raf|| CRAF

Gene Name

RAF1

Gene ID

5894

UniProt

P04049

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around aa.257~261 (S-T-S-T-P) derived from Human RAF.

Target Antigen

Raf1 (Ab-259)

Clonality

Polyclonal

Applications

WB, IHC

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 73kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Isotype

Rabbit IgG

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