Polyclonal Antibody to FBXL3 (Phospho-Ser320)
Substrate-recognition component of the SCF (FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF (FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF (FBXL3) complex is counteracted by the SCF (FBXL21) complex.
Product Specifications
Product Name Alternative
FBL3A|| FBXL3A
Gene Name
FBXL3
Gene ID
26224
UniProt
Q9UKT7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of serine 320 (S-V-S (p) -K-D) derived from Human FBXL3.
Target Antigen
FBXL3 (Phospho-Ser320)
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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