Polyclonal Antibody to MEK5 (phospho-Ser311/ Thr315)
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.
Product Specifications
Product Name Alternative
Map2k5
Gene Name
Map2k5
Gene ID
29568
UniProt
Q62862
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of Serine 311 and threonine 315 (V-N-S (p) I-A-K-T (p) -Y-V) derived from Rat MEK5.
Target Antigen
MEK5 (phospho-Ser311/ Thr315)
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 46kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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