Polyclonal Antibody to MARCKS (phospho-Ser170)
MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. Ramsden, J.J. (2000) Int. J. Biochem. Cell Biol. 32, 475-479. Graff, J. M. et al. (1989) J. Biol. Chem. 264, 21818-21823. Hartwig, J. H. et al. (1992) Nature 356, 618-622. Thelen, M. et al. (1991) Nature 351, 320-322.
Product Specifications
Product Name Alternative
MACS||80K-L||PKCSL||PRKCSL
Gene Name
MARCKS
Gene ID
4082
UniProt
P29966
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around phosphorylation site of Serine 170 (G-F-S (p) -F-K) derived from Human MARCKS.
Target Antigen
MARCKS (phospho-Ser170)
Clonality
Polyclonal
Applications
WB, IHC
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 80kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Isotype
Rabbit IgG
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