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Polyclonal Antibody to cofilin1 (phospho-Tyr139)

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Product Specifications

Product Name Alternative

CFL|| CFL1

Gene Name

CFL1

Gene ID

1072

UniProt

P23528

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of tyrosine 139 (N-C-Y (p) -E-E) derived from Human cofilin.

Target Antigen

Cofilin1 (phospho-Tyr139)

Clonality

Polyclonal

Applications

IHC

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 19kd, Immunohistochemistry: 1:50~1:100

Isotype

Rabbit IgG

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