Polyclonal Antibody to Alpha-catenin (Phospho-Ser641)
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation. Hwang, S.G. et al. (2005) J. Biol. Chem. 280, 12758-12765 Drees, F. et al. (2005) Cell 123, 903-915. Yamada, S. et al. (2005) Cell 123, 889-901. Kobielak, A. and Fuchs, E. (2004) Nat. Rev. Mol. Cell Biol. 5, 614-625.
Product Specifications
Product Name Alternative
Cadherin-associated protein|| Alpha E-catenin|| NY-REN-13 antigen
Gene Name
CTNNA1
Gene ID
1495
UniProt
P35221
Host
Rabbit
Reactivity
Mouse, Human
Immunogen
Peptide sequence around phosphorylation site of serine 641 (D-D-S (p) -D-F) derived from Human a-catenin.
Target Antigen
Alpha-catenin (Phospho-Ser641)
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 100kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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