Polyclonal Antibody to TrkB (Phospho-Tyr515)
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF) . Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
Product Specifications
Product Name Alternative
BDNF/NT-3 growth factors receptor precursor|| GP145-TrkB|| GP145-TrkB/GP95-TrkB|| NTRK2|| Trk-B
Gene Name
NTRK2
Gene ID
4915
UniProt
Q16620
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around phosphorylation site of tyrosine 515 (P-Q-Y (p) -F-G) derived from Human TrkB.
Target Antigen
TrkB (Phospho-Tyr515)
Clonality
Polyclonal
Applications
IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 140kd, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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