Polyclonal Antibody to SHP-2 (Phospho-Tyr580)
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Ferjoux G, et al. (2003) Mol Biol Cell. 2003 ; 14 (9) : 3911-3928. Shi ZQ, et al. (2000) Mol Cell Biol ; 20 (5) : 1526-1536. Li C, Friedman JM. (1999) Proc Natl Acad Sci U S A ; 96 (17) : 9677-9682 Manes S, et al. (1999) Mol Cell Biol ; 19 (4) : 3125-3135. Oh ES, et al. (1999) Mol Cell Biol; 19 (4) : 3205-3215.
Product Specifications
Product Name Alternative
PTN11|| PTP-1D|| PTP-2C|| PTP2C|| PTPN11
Gene Name
PTPN11
Gene ID
5781
UniProt
Q06124
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around phosphorylation site of tyrosine 580 (R-V-Y (p) -E-N) derived from Human SHP-2.
Target Antigen
SHP-2 (Phospho-Tyr580)
Clonality
Polyclonal
Applications
IHC, WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 72kd, Immunohistochemistry: 1:50~1:100
Isotype
Rabbit IgG
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