Polyclonal Antibody to PKC Delta (Phospho-Ser645)
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
Product Specifications
Product Name Alternative
KPCD|| PKC-delta|| PRKCD|| kinase PKC-delta|| nPKC-delta
Gene Name
PRKCD
Gene ID
5580
UniProt
Q05655
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Peptide sequence around phosphorylation site of serine 645 (R-L-S (p) -Y-S) derived from Human PKCd.
Target Antigen
PKC Delta (Phospho-Ser645)
Clonality
Polyclonal
Applications
WB, IHC
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 78kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Isotype
Rabbit IgG
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