Polyclonal Antibody to Gab1 (Phospho-Tyr627)
The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
Product Specifications
Product Name Alternative
Growth factor receptor bound protein 2-associated protein 1
Gene Name
GAB1
Gene ID
2549
UniProt
Q13480
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Peptide sequence around phosphorylation site of tyrosine 627 (V-E-Y (p) -L-D) derived from Human Gab1.
Target Antigen
Gab1 (Phospho-Tyr627)
Clonality
Polyclonal
Applications
WB, IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 110kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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