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Polyclonal Antibody to Gab1 (Phospho-Tyr627)

The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

Product Specifications

Product Name Alternative

Growth factor receptor bound protein 2-associated protein 1

Gene Name

GAB1

Gene ID

2549

UniProt

Q13480

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Peptide sequence around phosphorylation site of tyrosine 627 (V-E-Y (p) -L-D) derived from Human Gab1.

Target Antigen

Gab1 (Phospho-Tyr627)

Clonality

Polyclonal

Applications

WB, IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 110kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Isotype

Rabbit IgG

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