Polyclonal Antibody to CaMKII (Phospho-Thr286)
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity Pak JH, et al. Proc Natl Acad Sci U S A. 2000 Oct 10; 97 (21) : 11232-11237 Hudmon A, et al. J Cell Biol. Author manuscript; available in PMC 2006 May 7 Miller P, et al. PLoS Biol. 2005 Apr; 3 (4) : e107 Runyan JD, et al. Learn Mem. 2005 Mar; 12 (2) : 103-110.
Product Specifications
Product Name Alternative
CAMKA
Gene Name
CAMK2A
Gene ID
815
UniProt
Q9UQM7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of threonine 286 (Q-E-T (p) -V-D) derived from Human CaMKII.
Target Antigen
CaMKII (Phospho-Thr286)
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 50kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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