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Polyclonal Antibody to p70 S6 Kinase (Phospho-Ser424)

Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.

Product Specifications

Product Name Alternative

KS6B1|| P70-S6K|| RPS6KB1|| S6K

Gene Name

RPS6KB1

Gene ID

6198

UniProt

P23443

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of serine 424 (P-V-S (p) -P-V) derived from Human p70 S6 Kinase.

Target Antigen

P70 S6 Kinase (Phospho-Ser424)

Clonality

Polyclonal

Applications

WB, IHC, IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 70 85 kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Isotype

Rabbit IgG

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