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Polyclonal Antibody to Connexin 43 (phospho-Ser367)

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Joell L. Solan1, et al. (2003) Cell Science 116: 2203-2211 Satoshi Matsushita, et al. (2006) Histochemistry and Cytochemistry 54 (3) : 343-353, Xiaoyong Bao, et al. (2004) Cell Physiol 286: C647-C654 W. E. I. Li, et al. (1998) European Journal of Neuroscience 10: 2444

Product Specifications

Product Name Alternative

CX43|| CXA1|| CXN-43|| GJA1

Gene Name

GJA1

Gene ID

2697

UniProt

P17302

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of serine 368 (R-A-S (p) -S-R) derived from Human Connexin 43.

Target Antigen

Connexin 43 (phospho-Ser367)

Clonality

Polyclonal

Applications

WB, IHC

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 43kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Isotype

Rabbit IgG

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