Polyclonal Antibody to p70 S6 Kinase (Phospho-Thr421)
Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.
Product Specifications
Product Name Alternative
KS6B1|| P70-S6K|| RPS6KB1|| S6K
Gene Name
RPS6KB1
Gene ID
6198
UniProt
P23443
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of threonine 421 (P-R-T (p) -P-V) derived from Human p70 S6 Kinase.
Target Antigen
P70 S6 Kinase (Phospho-Thr421)
Clonality
Polyclonal
Applications
WB, IHC, IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 70 85 kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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