Polyclonal Antibody to p44/42 MAP Kinase (Phospho-Tyr204)
Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2) . Phosphorylates SPZ1 TETE HANNKEN, et al. (2000) Am Soc Nephrol 11:1387-1397 Omar D. PerezNature et al. (2002) Biotechnology 20: 155 - 162 Jingui Yu, et al. (2005) Anesth Analg 101: 315-321 Hironobu Ihn et al. (2000) Immunology 165: 2149-2155
Product Specifications
Product Name Alternative
ERK1||ERT2||ERK-1||PRKM3||P44ERK1
Gene Name
MAPK3
Gene ID
5595
UniProt
P27361
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of tyrosine 204 (T-E-Y (p) -V-A) derived from Human p44/42 MAP Kinase.
Target Antigen
P44/42 MAP Kinase (Phospho-Tyr204)
Clonality
Polyclonal
Applications
WB, IHC, IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 42 44 kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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TMPPE, ID (TMPPE, Transmembrane protein with metallophosphoesterase domain) (PE)
