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EGFR (Phospho-Tyr1197) Antibody

Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin. Modification: Phospho-Tyr1197

Product Specifications

Product Name Alternative

ERBB1; Receptor protein-tyrosine kinase ErbB-1; kinase EGFR, Proto-oncogene c-ErbB-1

Gene Name

EGFR

Gene ID

1956

UniProt

P00533

Host

Rabbit

Reactivity

Rat, Mouse, Human

Immunogen

Peptide sequence around phosphorylation site of tyrosine 1197 (A-E-Y (p) -L-R) derived from Human EGFR

Target Antigen

EGFR

Clonality

Polyclonal

Applications

IHC, WB

Purification

Affinity-chromatography

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store at 4°C; For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 175kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

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