EGFR (Phospho-Tyr1197) Antibody
Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin. Modification: Phospho-Tyr1197
Product Specifications
Product Name Alternative
ERBB1; Receptor protein-tyrosine kinase ErbB-1; kinase EGFR, Proto-oncogene c-ErbB-1
Gene Name
EGFR
Gene ID
1956
UniProt
P00533
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around phosphorylation site of tyrosine 1197 (A-E-Y (p) -L-R) derived from Human EGFR
Target Antigen
EGFR
Clonality
Polyclonal
Applications
IHC, WB
Purification
Affinity-chromatography
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at 4°C; For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 175kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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