Polyclonal Antibody to 4E-BP1 (Phospho-Thr36)
Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Product Specifications
Product Name Alternative
BP-1|| 4EBP1|| 4E-BP1|| PHAS-I
Gene Name
EIF4EBP1
Gene ID
1978
UniProt
Q13541
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of threonine 36 (S-T-T (p) -P-G) derived from Human 4E-BP1.
Target Antigen
4E-BP1 (Phospho-Thr36)
Clonality
Polyclonal
Applications
WB, IHC
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 18kd, , Western blotting: 1:500, Immunohistochemistry: 1:50~1:100
Isotype
Rabbit IgG
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