Polyclonal Antibody to Tyrosine Hydroxylase (Phospho-Ser40)
The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Product Specifications
Product Name Alternative
TY3H|| TYH|| Tyrosine 3-hydroxylase|| tyrosine hydroxylase
Gene Name
TH
Gene ID
7054
UniProt
P07101
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around phosphorylation site of serine 40 (R-Q-S (p) -L-I) derived from Human Tyrosine Hydroxylase (TH) .
Target Antigen
Tyrosine Hydroxylase (Phospho-Ser40)
Clonality
Polyclonal
Applications
IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 55-60 kd, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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