Polyclonal Antibody to Synaptotagmin 1/2 (Phospho-Thr202/199)
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105 (10) :3992-7. Cnops L, et al. Cereb Cortex. 2008 May; 18 (5) :1221-31. Lynch KL, et al. Mol Biol Cell. 2007 Dec; 18 (12) :4957-68.
Product Specifications
Product Name Alternative
SYT1/2|| SytI/II|| Synaptotagmin I/II|| P65|| SYT
Gene Name
SYT1
Gene ID
6857
UniProt
P21579/Q89I0
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around phosphorylation site of threonine 202/199 (R-K-T (p) -L-N) derived from Human Synaptotagmin 1/2.
Target Antigen
Synaptotagmin 1/2 (Phospho-Thr202/199)
Clonality
Polyclonal
Applications
IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 46kd, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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