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Polyclonal Antibody to Synaptotagmin 1 (Phospho-Ser309)

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105 (10) :3992-7. Cnops L, et al. Cereb Cortex. 2008 May; 18 (5) :1221-31. Lynch KL, et al. Mol Biol Cell. 2007 Dec; 18 (12) :4957-68.

Product Specifications

Product Name Alternative

SYT1|| SytI|| Synaptotagmin I|| P65|| SYT

Gene Name

SYT1

Gene ID

6857

UniProt

P21579

Host

Rabbit

Reactivity

Rat, Mouse, Human

Immunogen

Peptide sequence around phosphorylation site of serine 309 (G-L-S (p) -D-P) derived from Human Synaptotagmin 1.

Target Antigen

Synaptotagmin 1 (Phospho-Ser309)

Clonality

Polyclonal

Applications

IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 46kd, Immunofluorescence: 1:100~1:200

Isotype

Rabbit IgG

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