Polyclonal Antibody to p27Kip1 (Phospho-Thr187)
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.
Product Specifications
Product Name Alternative
CDKN1B|| CDN1B|| Cyclin-dependent kinase inhibitor 1B|| Cyclin-dependent kinase inhibitor p27|| KIP1
Gene Name
CDKN1B
Gene ID
1027
UniProt
P46527
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around phosphorylation site of threonine 187 (E-Q-T (p) -P-K) derived from Human p27Kip1.
Target Antigen
P27Kip1 (Phospho-Thr187)
Clonality
Polyclonal
Applications
WB, IHC
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 27kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Isotype
Rabbit IgG
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