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Polyclonal Antibody to MEK1/MEK2 (Phospho-Ser217/Ser221)

Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.

Product Specifications

Product Name Alternative

ERK activator kinase 1/ERK activator kinase2|| MAP kinase kinase 1/MAP kinase kinase 2|| MAP2K1/MAP2K1|| MAPK/ERK kinase 1/MAPK/ERK kinase 2|| MAPKK 1/MAPKK 1

Gene Name

MAP2K1

Gene ID

5604

UniProt

Q02750

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of serine 217/221 (I-D-S (p) -M-A) derived from Human MEK1/MEK2.

Target Antigen

MEK1/MEK2 (Phospho-Ser217/Ser221)

Clonality

Polyclonal

Applications

IHC, WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 45kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Isotype

Rabbit IgG

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