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Polyclonal Antibody to HSF1 (Phospho-Ser307)

DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. Guettouche T, et al. (2005) BMC Biochem ; 6 (1) : 4 Wang X, et al. (2003) Mol Cell Biol ; 23 (17) : 6013-6026 Jolly C, et al. (1999) Proc Natl Acad Sci USA; 96 (12) : 6769-6774.

Product Specifications

Product Name Alternative

HSTF 1

Gene Name

HSF1

Gene ID

3297

UniProt

Q00613

Host

Rabbit

Reactivity

Human

Immunogen

Peptide sequence around phosphorylation site of serine 307 (P-Q-S (p) -P-R) derived from Human HSF1.

Target Antigen

HSF1 (Phospho-Ser307)

Clonality

Polyclonal

Applications

WB, IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 82kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Isotype

Rabbit IgG

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