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Polyclonal Antibody to NMDAR2B (phospho-Tyr1474)

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Babb TL et al.Epilepsy Res. 2005 Mar-Apr;64 (1-2) :23-30 Chazot PL. Curr Med Chem. 2004 Feb;11 (3) :389-96 Kakegawa W, et al.Eur J Neurosci. 2003 Feb;17 (4) :887-91

Product Specifications

Product Name Alternative

GRIN2B|| NMDE2|| NME2|| NR2B|| NR3

Gene Name

GRIN2B

Gene ID

2904

UniProt

Q13224

Host

Rabbit

Reactivity

Rat, Mouse, Human

Immunogen

Peptide sequence around phosphorylation site of Tyr1474 (H-V-Y (p) -E-K) derived from Human NMDAR2B.

Target Antigen

NMDAR2B (phospho-Tyr1474)

Clonality

Polyclonal

Applications

WB, IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 190kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Isotype

Rabbit IgG

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