Polyclonal Antibody to DNA PKcs (Phospho-Thr2609)
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK) . The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties
Product Specifications
Product Name Alternative
DNPK1|| PRKD|| PRKDC|| XRCC7|| P460
Gene Name
PRKDC
Gene ID
5591
UniProt
P78527
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around phosphorylation site of threonine 2609 (V-E-T (p) -Q-A) derived from Human DNA-PK.
Target Antigen
DNA PKcs (Phospho-Thr2609)
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 450kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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