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Polyclonal Antibody to Zap-70 (Phospho-Tyr493)

Plays a role in T-cell development and lymphocyte activation. Essential for TCR-mediated IL-2 production. Isoform 1 induces TCR-mediated signal transduction, isoform 2 does not.

Product Specifications

Product Name Alternative

70 kDa zeta-associated protein|| SRK|| Syk-related tyrosine kinase|| ZA70|| ZAP-70

Gene Name

ZAP70

Gene ID

7535

UniProt

P43403

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of tyrosine 493 (S-Y-Y (p) -T-A) derived from Human Zap-70.

Target Antigen

Zap-70 (Phospho-Tyr493)

Clonality

Polyclonal

Applications

WB, IHC

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 70kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Isotype

Rabbit IgG

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