Polyclonal Antibody to MKK3 (Phospho-Ser189)
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Wang W, et al. (2002) Mol Cell Biol ; 22 (10) : 3389-403. Raingeaud J, et al. (1996) Mol Cell Biol; 16 (3) : 1247-55.
Product Specifications
Product Name Alternative
MAP kinase kinase 3|| MAP2K3|| MAPK/ERK kinase 3|| MAPKK 3|| MEK3
Gene Name
MAP2K3
Gene ID
5606
UniProt
P46734
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of serine 189 (V-D-S (p) -V-A) derived from Human MKK3.
Target Antigen
MKK3 (Phospho-Ser189)
Clonality
Polyclonal
Applications
WB, IHC, IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 40kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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