Polyclonal Antibody to VEGFR2 (Phospho-Tyr1214)
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions Lamalice L, et al. (2004) . Oncogene.23 (2) : 434-445. Takahashi T, et al. (2001) . EMBO J .20 (11) : 2768-2778.
Product Specifications
Product Name Alternative
FLK1|| KDR|| VGFR2|| VGR2|| kinase insert domain receptor
Gene Name
KDR
Gene ID
3791
UniProt
P35968
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of tyrosine 1214 (F-H-Y (p) -D-N) derived from Human VEGFR2.
Target Antigen
VEGFR2 (Phospho-Tyr1214)
Clonality
Polyclonal
Applications
WB, IHC, IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 230kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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