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Polyclonal Antibody to VEGFR2 (Phospho-Tyr1175)

Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

Product Specifications

Product Name Alternative

FLK1|| KDR|| VGFR2|| VGR2|| kinase insert domain receptor

Gene Name

KDR

Gene ID

3791

UniProt

P35968

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of tyrosine 1175 (K-D-Y (p) -I-V) derived from Human VEGFR2.

Target Antigen

VEGFR2 (Phospho-Tyr1175)

Clonality

Polyclonal

Applications

IHC, IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 230kd, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Isotype

Rabbit IgG

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