Polyclonal Antibody to HER2 (Phospho-Tyr1221/Tyr1222)
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-a and amphiregulin. Marone R, et al. (2004) Nat Cell Biol; 6 (6) : 515-22. Ren Z, et al. (2002) J Biol Chem; 277 (41) : 38486-93.
Product Specifications
Product Name Alternative
C-erbB-2|| ErbB2
Gene Name
ERBB2
Gene ID
2064
UniProt
P04626
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around phosphorylation site of tyrosine1221/1222 (N-L-Y (p) -Y (p) -W) derived from Human HER2.
Target Antigen
HER2 (Phospho-Tyr1221/Tyr1222)
Clonality
Polyclonal
Applications
WB, IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 185kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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