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Polyclonal Antibody to Estrogen Receptor- Alpha (Phospho-Ser118)

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ramsauer VP, et al. (2003) J Biol Chem; 278 (32) : 30142-7. Jepson S, et al. (2002) Oncogene; 21 (49) : 7524-32. Ren Z, et al. (2002) J Biol Chem; 277 (41) : 38486-93. Eppenberger-Castori S, et al. (2001) J Clin Oncol; 19 (3) : 645-56.

Product Specifications

Product Name Alternative

ER|| ESR|| ESR1|| ESTR|| ESTRA

Gene Name

ESR1

Gene ID

2099

UniProt

P03372

Host

Rabbit

Reactivity

Human

Immunogen

Peptide sequence around phosphorylation site of serine 118 (Q-L-S (p) -P-F) derived from Human Estrogen Receptor-a.

Target Antigen

Estrogen Receptor- Alpha (Phospho-Ser118)

Clonality

Polyclonal

Applications

WB, IHC, IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 66kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Isotype

Rabbit IgG

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