Polyclonal Antibody to BCL-2 (Phospho-Thr56)
Suppresses apoptosis in a variety of cell systems includingfactor-dependent lymphohematopoietic and neural cells. Regulates cell death bycontrolling the mitochondrial membrane permeability. Appears to function in a feedbackloop system with caspases. Inhibits caspase activity either by preventing the release ofcytochrome c from the mitochondria and/or by binding to the apoptosis-activatingfactor (APAF-1) .
Product Specifications
Product Name Alternative
Bcl-2||PPP1R50
Gene Name
BCL2
Gene ID
596
UniProt
P10415
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around phosphorylation site of threonine 56 (G-H-T (p) -P-H) derived from Human BCL-2.
Target Antigen
BCL-2 (Phospho-Thr56)
Clonality
Polyclonal
Applications
IHC
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 26kd, Immunohistochemistry: 1:50~1:100
Isotype
Rabbit IgG
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