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Polyclonal Antibody to STAT3 (Phospho-Tyr705)

Transcription factor that binds to the interleukin-6 (IL-6) -responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Fan G, et al. (2003) J Biol Chem. 278 (52) : 52432-52436. Barry FA, et al. (2003) FEBS Lett. 553 (1-2) : 173-178. Welsh, et al. (1996) Trends Cell Biol. 6: 274-279. Srivastava A K, et al. (1998) Mol Cell Biochem. 182: 135-141.

Product Specifications

Product Name Alternative

APRF|| Acute-phase response factor|| HIES

Gene Name

STAT3

Gene ID

6774

UniProt

P40763

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of tyrosine 705 (A-P-Y (p) -L-K) derived from Human STAT3.

Target Antigen

STAT3 (Phospho-Tyr705)

Clonality

Polyclonal

Applications

WB, IHC, IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 88kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Isotype

Rabbit IgG

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