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Polyclonal Antibody to HNF4 Alpha (Phospho-Ser304)

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 a, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants.

Product Specifications

Product Name Alternative

HNF4|| TCF|| MODY|| HNF4A

Gene Name

HNF4A

Gene ID

3172

UniProt

P41235

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around phosphorylation site of serine 304 (L-R-S (p) -Q-V) derived from Human HNF4a.

Target Antigen

HNF4 Alpha (Phospho-Ser304)

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 52kd, Western blotting: 1:1000

Isotype

Rabbit IgG

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