Polyclonal Antibody to NF-KB-p105/p50 (Phospho-Ser893)
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NF-KB1/p105, NF-KB1/p50, REL and NF-KB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
Product Specifications
Product Name Alternative
KBF1|| NF-kB1|| NFkappaB
Gene Name
NF-kB1
Gene ID
4790
UniProt
P19838
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around aa.891~895 (A-S-S-P-V) derived from Human NF-KB-p105.
Target Antigen
NF-KB-p105/p50 (Phospho-Ser893)
Clonality
Polyclonal
Applications
IHC, IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Immunohistochemistry 1:50~1:100 Immunofluorescence 1:100~1:200
Isotype
Rabbit IgG
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
