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Anti-TNF-alpha Monoclonal Antibody (Clone:MAb11) -HRP Conjugated

Selected Variant

30-1490-HRP-0.1

Size: 0.1 mg

Specificity: The mouse monoclonal antibody MAb11 recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha) . Description: TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.

Product Specifications

Product Name Alternative

Tumor necrosis factor, Cachectin , Tumor necrosis factor ligand superfamily member 2, TNFA, DIF, TNLG1F

Gene Name

TNF

Gene ID

7124

UniProt

P01375

Host

Mouse

Reactivity

Pig, Human, Non-Human Primates

Immunogen

Recombinant human TNF-alpha

Target Antigen

TNF-alpha

Clonality

Monoclonal

Clone

MAb11

Applications

IHC-Fr, ELISA, FACS

Purification

Purified antibody is conjugated with activated horseradish peroxidase (HRP) of high specific enzyme activity under optimum conditions and unconjugated antibody and free HRP are removed by size-exclusion chromatography.

Components

Concentration: 0.2 mg/mL, Stabilizing phosphate buffered saline (PBS), pH 7.4, 0.01% thimerosal

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Applications Notes

ELISA: HRP-conjugated MAb11 can be used as a detection antibody in combination with capture antibody MAb1.

Isotype

Mouse IgG1 kappa

Conjugate

HRP

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