PE Conjugated Anti-Human CD226 Mab (Clone:11A8)
CD226 is a type I transmembrane glycoprotein, which is expressed after activation on NK cells, platelets, monocytes, and some T cells. Its expression is increased in patients suffering from some autoimmune diseases or viral infections. CD226 is being phosphorylated on its cytoplasmic tail and interacts with LFA-1 complex (CD11a/CD18), resulting in calcium-independent intercellular contacts. Ligands for CD226 are CD155 and CD112.
Product Specifications
Product Name Alternative
DNAM1, PTA1, TLiSA1
Gene Name
CD226
Gene ID
10666
UniProt
Q15762
Host
Mouse
Reactivity
Human, Non-Human Primates
Target Antigen
CD226
Clonality
Monoclonal
Clone
11A8
Applications
FACS
Purification
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Components
Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Applications Notes
Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Isotype
Mouse IgG1 kappa
Conjugate
PE
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