Anti-Human CD226 Monoclonal Antibody (Clone:11A8)
CD226 is a type I transmembrane glycoprotein, which is expressed after activation on NK cells, platelets, monocytes, and some T cells. Its expression is increased in patients suffering from some autoimmune diseases or viral infections. CD226 is being phosphorylated on its cytoplasmic tail and interacts with LFA-1 complex (CD11a/CD18), resulting in calcium-independent intercellular contacts. Ligands for CD226 are CD155 and CD112.
Product Specifications
Product Name Alternative
DNAM1, PTA1, TLiSA1
Gene ID
10666
UniProt
Q15762
Host
Mouse
Reactivity
Human, Non-Human Primates
Target Antigen
CD226
Clonality
Monoclonal
Clone
11A8
Applications
FACS
Purification
Purified by protein-A affinity chromatography
Format
Purified
Components
1mg/mL, Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/mL.
Isotype
Mouse IgG1 kappa
Conjugate
Unconjugated
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