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Anti-CD163 Monoclonal Antibody (Clone:GHI/61) PerCP-Cy5.5

CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.

Product Specifications

Product Name Alternative

CD163||M130

Gene Name

CD163

Gene ID

9332

UniProt

Q86VB7

Host

Mouse

Reactivity

Human

Immunogen

Hairy cell leukemia cells

Target Antigen

CD163

Clonality

Monoclonal

Clone

GHI/61

Applications

FACS

Purification

Purified by protein-A affinity chromatography

Storage Conditions

Store at 2-8°C. Do not freeze.

Isotype

Mouse IgG1

Conjugate

APC/CY5.5

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